Systems Biology and Cell Signaling: A Comprehensive Review
Asian Journal of Basic and Applied Sciences,
2023
Autour(s)
- Tomiloba Olutola, John Balen, Vivian Lotisa, Akaw Johnima, Ibrina Browndi
Abstract
The cellular signaling system is a highly interconnected and dynamic network that is subject to complex regulation. The emerging field of systems biology has enabled the study of the cellular signaling system at a global level, using high-throughput experimental techniques and mathematical modeling. In this article, we provide a comprehensive review of the application of systems biology approaches to the study of cell signaling, including molecular network analysis, mathematical modeling, and the integration of experimental techniques. We also discuss the challenges and limitations associated with these approaches and their potential for the development of novel therapeutic interventions.